PROGRAM
8.15am
Registration
8.50 – 9.15am
Daniel Dunia & Annie Lannuzel (organizers)
Yazdan Yazdanpanah (Director, thematic institute I3M) & Denis Vivien (Director, thematic institute Neuro)
Welcome notes
Session 1. Virus & Cells – Approaches to study the molecular and cellular biology of neuroinfections
Chairman: Raphael Gaudin
9.15 – 10.00am
Carl Sellgren – Karolinska Institutet, Stockholm (Sweden)
“Using human brain organoids to model neurotropic viruses”
10.00 – 10.25am
Jean-Pierre Levraud – NeuroPSI Saclay (France)
“A direct view of alphavirus invasion of the zebrafish brain”
10.25 – 10.40am
Katharina Schiering – University Medical Center Hamburg – Eppendorf (Germany)
“JC-Polyomavirus infection of cerebral organoid slices at the air-liquid interface”
10.40 – 11.10am
Coffee break
11.10 – 11.25am
Gaëtan Ligat – Infinity, Toulouse (France)
“YBX1 drives HCMV replication in glioblastoma”
11.25 – 11.40am
David Noyvert – Department of Pathology, Cambridge (UK)
“Signal Peptide Peptidase is an Essential Host Factor for Replication of Neurotropic Human Astroviruses”
11.40 – 11.55am
Paula Leupold – Max-Delbrück Center for Molecular Medicine (MDC-BIMSB, Germany)
“Studying WNV and HSV-1 infection in brain organoids with spatial transcriptomics”
11.55 – 12.20pm
Anna Överby – Umeå Universitet (Sweden)
“Understanding viral tropism using whole brain imaging and single nuclei RNA sequencing”
12.20 – 2.00pm
Lunch
1.00 – 2.00pm
Poster session 1
Session 2. Virus & Neuropathogenesis – Neurologic and neurocognitive dysfunctions upon infection
Chairman: Daniel Dunia
2.00 – 2.45pm
Robyn Klein – Western University, London (Canada)
“Emerging RNA viruses and post-infectious cognitive dysfunction”
2.45 – 3.10pm
Debby van Riel – Erasmus MC, Rotterdam (the Netherlands)
“The neuropathogenesis of influenza”
3.10 – 3.25pm
Jules Bouget – IRIM, CNRS & Univ Montpellier (France)
“Pharmacological targeting of Bunyavirus-induced synaptic impairment prevents neuronal hyperexcitability”
3.25 – 3.50pm
Patricia Beltrão-Braga – Univ São Paulo (Brazil)
“Decoding Neuroviral Impact on Brain Development Using Human iPSC-Derived Organoids”
3.50 – 4.15pm
Coffee break
4.15 – 4.30pm
Isis Leguay – Virologie et Immunologie Moléculaires, INRAE, Jouy-en-Josas (France)
“Neurotropism characterisation of PVM: a Pneumovirus naturally infecting mice”
4.30 – 4.45pm
Michalina Bartak – Institute of Veterinary Medicine, Warsaw University of Life Sciences (Poland)
“Molecular mechanisms of Sialodacryoadenitis Virus neuropathogenicity in an in vitro primary cell culture model of the central nervous system”
4.45 – 5.00pm
Sofie Nyström – IFM-Chemistry, Linköping (Sweden)
“Virus protein amyloids as triggers of neurodegenerative disease”
5.00 – 5.15pm
Dennis Freisem – Ulm University (Germany)
“The role of HSV-1 in the molecular pathology of ALS”
5.15 – 5.30pm
Alba Pérez Arribas – University of Copenhagen (Denmark)
“The contribution of HSV-1 to the development of neurodegeneration through HIF-1ɑ”
5.30 – 7.30pm
Social event (onsite registration)
8.00pm
Dinner for invited speakers and organizers
9.00 – 10.15am
Thematic round tables
1. Virus & Cells;
2. Virus & Pathogenicity;
3. Virus & Immunity
10.30 – 11.00am
Coffee break
11.00 – 11.45am
Structured write-up
11.45 – 12.30pm
Lunch
12.30 – 13.30pm
Poster session 2
Session 3. Virus & Immunity – Mechanisms associated with neuroinflammation and antiviral responses
Chairman: Cyrille Mathieu
1.30 – 2.15pm
Søren R. Paludan – Aarhus Univ (Denmark)
“Innate antiviral responses in the brain: host defense and immunopathology”
2.15 – 2.40pm
Réjane Rua – CIML Marseille (France)
“Brain borders take center stage: role of skull and meningeal myeloid cells in controlling neuroinflammation”
2.40-2.55pm
Jinte Middeldorp – Biomedical Primate Research Centre, Rijswijk (The Netherlands)
“Multimodal evidence of SARS-CoV-2–induced neuroinflammation and neurodegeneration in non-human primates”
2.55-3.20pm
Muriel Coulpier – UMR of Virology, INRAE, Maisons-Alfort (France)
“Modeling Neural Infection by Emerging Arboviruses to Advance Antiviral Discovery”
3.20-3.35pm
Michelle Gellhorn Serra – Institute of Virology, Marburg Univ (Germany)
“Establishment of murine and human in vitro blood-brain barrier models to study CNS entry of Ebola virus and Nipah virus via the hematogenous route”
3.35 – 4.00pm
Keshia Kroh – Erasmus MC, Rotterdam (the Netherlands)
“Keratinocytes as entry portals for rabies virus neuroinvasion”
4.00 – 4.15pm
Yonatan Ganor – Institut Cochin, Paris (France)
“Neuroimmune interplay between nociceptor neurons and immune Langerhans cells in HSV-2 and HIV-1 co-infection”
4.15 – 4.30pm
Concluding remarks & Best poster/oral presentation awards
4.30 – 6.00pm
Closed-door organizing committee meeting